Asian Pacific Journal of Tropical Biomedicine
Isolation and identification of compounds from Phaleria macrocarpa (Scheff.) Boerlfruit extract
- Article
- Figures
- Metrics
- Preview PDF
- Reference
- Related
- Cited by
- Materials
Abstract:
Objective: To identify and isolate the chemical compounds of Phaleria macrocarpa (P. macrocarpa) fruit ethanolic extract. Methods: Dried fruit of P. macrocarpa was extracted with 90% ethanol and partitioned between n-hexane/H 2 O and ethyl acetate/H 2 O. The organic layer was fractionated by various stationary phase and identified by using combined data of 1D [(proton nuclear magnetic resonance (NMR), carbon-13 NMR)], 2D-NMR (heteronuclear multiple- quantum correlation and heteronuclear multiple-bond correlation), and mass spectrum. Results: Purification of n-hexane and ethyl acetate fractions from ethanolic extract of P. macrocarpa fruit resulted in isolation of nine compounds. Conclusions: A new compound was isolated and identified as glyceryl pentacosanoate. Also, two xanthones, which are 1,7-dihydroxy-3,6-dimethoxyxanthone and 1,6,7- trihydroxy-3-methoxyxanthone, are firstly reported to be isolated from P. macrocarpa.
Keywords:
Project Supported:
Supported by PT Dexa Medica with grant number 120/IMC/DLBS/2014.
Clc Number:
Publication ethics
Academic misconduct statement
Mobile website
