目的:探讨3D打印结合腹直肌旁入路下手术治疗骨盆骨折的创伤及应激程度。方法:收集在医院进行手术治疗的骨盆骨折患者50例,随机分为对照组、观察组各25例。对照组接受腹直肌旁入路下手术治疗,观察组接受3D打印结合腹直肌旁入路下手术治疗。对比两组患者围术期炎症反应、凝血功能及应激程度的差异。结果:术前24 h,两组的炎症反应、凝血功能及应激程度差异无统计学意义(P＞0.05)。术后24 h,两组血清中IL-1、TNF-α、CRP、FIB、D-D、Cor、AngⅡ、NE的含量均高于术前24 h且观察组血清中IL-1、TNF-α、CRP、FIB、D-D、Cor、AngⅡ、NE的含量均低于对照组。结论:骨盆骨折患者接受3D打印结合腹直肌旁入路下手术治疗,可有效减轻手术创伤程度并降低全身应激反应。

Objective: To study the trauma and stress level of the pelvic fracture treated by 3D printing combined with lateral rectus abdominis approach surgery. Methods: A total of 50 patients with pelvic fractures who were treated in the hospital between July 2015 and Jun 2017 were collected anddivided into control group (n=25) and observation group (n=25) by random number table method. Control group underwent lateral rectus abdominis approach surgery, and the observation group received 3D printingcombined with lateral rectus abdominis approach surgery. The differences in perioperative inflammatory response, coagulation function and stress degree were compared between the two groups. Results:24 h before surgery, the differences in inflammatory response, coagulation function and stress degree were not statistically significant between the two groups (P＞0.05). 24 h after surgery, serum IL-1, TNF-α, CRP, FIB, D-D, Cor, AngⅡ and NE levels of both groups of patients were higher than those 24 h before surgery, and serum IL-1, TNF-α, CRP, FIB, D-D, Cor, AngⅡ and NE levels of observation group were lower than those of control group. Conclusion: 3D printing combined with lateral rectus abdominis approach surgery can effectively reduce the degree of surgical trauma and reduce the systemic stress response in patients with pelvic fracture.

R683.3

2016年南沙市科技计划项目(2016MS005)