Relationship between R5 parameters such as pulse shock pulmonary function test and MEFV and severity of chronic cough in children aged 3 to 5 years old
Objective: To investigate the relationship between the parameters of pulse oscillating lung function (IOS), airway viscosity resistance (R5), and maximum expiratory flow-volume curve (MEFV), and the severity of chronic cough in children aged 3 to 5 years. Methods: Eighty children with chronic cough who were diagnosed or treated in our hospital from March 2017 to March 2018 were selected as the study group, and 50 healthy children who underwent physical examination in our hospital were selected as the control group. The child's asthma control test (C-ACT) was used to assess the severity of the disease in the child. MEFV test scores in the two groups included the ratio of forced expiratory volume to forced vital capacity in the first second (FEV1/FVC) and peak expiratory flow (PEF). The reactance value (X5) at R5, the resonance frequency (Fres), and the oscillation frequency of 5 Hz was detected by IOS. The relationship between ACT scores and MEFV and IOS indicators was analyzed by Pearson correlation. The receiver operating characteristic (ROC) curve was used to evaluate the diagnostic value of MEFV and IOS indicators for chronic cough. Results: The C-ACT score of the severe group was significantly lower than that of the control group (P<0.05). FEV1/ FVC and PEF were lower in the mild and severe groups than in the control group. The severe group was lower than the mild group (P<0.05). Fres, R5 and X5 in the mild and severe groups were significantly higher than the control group, and the severe group was higher than the mild group (P<0.05). FEV1/ FVC and PEF were positively correlated with C-ACT score (P<0.05). There was a negative correlation between Fres, R5 and X5 and C-ACT score (P<0.05). Fres, R5 and X5 showed significant negative correlations with FEV1/FVC and PEF, respectively (P<0.05). R5 has a self-high ROC value of 0.938, followed by Fres, which is 0.917. And the value of IOS diagnostic indicators are higher than MEFV indicators. Conclusion: In children with chronic cough, FEV1/ FVC and PEF decreased while Fres, R5 and X5 increased, and Fres, R5 and X5 had a higher correlation with the severity of cough symptoms, and ROC analysis also showed that R5 was for children aged 3 to 5 years. Chronic cough has the highest diagnostic value.
Science and Technology Research and Development Plan of Qinhuangdao. Province No:201502A179.